The sheer size of the Airbus A380 means that its operators can only truly make it work on high-density hub-and-spoke routes where demand is strong enough to consistently fill the double-decker widebody quadjet. While no US airline has ever flown the superjumbo, plenty of other operators do serve stateside destinations with these behemoths. However, over the years, certain Americanairports have lost their A380 connections altogether.